ABSTRACT
Objective:Comparison of commercially available three HIV antibody detection kit for HIV infection,found as early HIV infection provides a reference method.Methods:By using two fourth generation HIV Kit ( Murex HIV Ag/Ab Kit:British Abbott company production numbers for A;Holland Organon company Vironostika HIV Uni-Form II Ag/Ab Kit:No.B;) a third generation HIV Kit ( British Abbott company produced Murex HIV-1.2.O Kit:No.C) and P24 antigen detection kit for 3 863 blood samples and BBI positive blood winding detection,sensitivity analysis,the specificity for the two fourth generation HIV kit for detecting,at the same time analysis of three kinds of antibody detection kit for detection of HIV infection window period of time whether the advance.Results:A kit,B were all positive blood samples from 54 patients with HIV infection,the sensitivity of A detection kit=100%,the specificity =99.61%, the rate of missed diagnosis=0, misdiagnosis rate=0.39%;the sensitivity of B detection kit=100%, the specificity =99.37%,the rate of missed diagnosis=0,misdiagnosis rate=0.63%;reagent A and B detection results are compared,the results did not show significant difference (P>0.05) ;A kit,B kit respectively compared with C reagent detection window period ahead of 5.5 and 3.7 d,but compared with P24 antigen kit detection window period was a lag of 4.25 to 6.05 d.Conclusion:In this study,the ability of two fourth generation HIV kit for detection of HIV infection in the strong sensitivity,reached 100%,but can be HIV infection window period in advance,to ensure the safe use of blood.